Prolonged treatment of hypertension with a thiazide diuretic, however, was associated with a more significant incidence of neovascular AMD, possibly due to the known phototoxic effects of thiazide diuretics (De la Marnierre 2003)
The [GSH]/[GSSG] ratio is used since it is considered an indicator of antioxidant capacity 37
When to speak to your GP Contact your GP or prescriber if you experience: Persistent stomach pain, especially if youre taking NSAIDs regularly Blood in your vomit or stools, or black tarry stools Severe constipation that doesnt respond to increased fluids and fibre, particularly if youre also taking codeine Reduced urine output or dark-coloured urine, which could suggest dehydration or kidney strain Pain that isnt adequately controlled by over-the-counter painkillers Severe nausea or vomiting that prevents you from taking your regular medications Any new or worsening side effects after starting a painkiller alongside Wegovy Regular painkiller use for a chronic condition that hasnt been reviewed recently If you experience severe abdominal pain, vomiting blood, or signs of bowel obstruction (complete inability to pass wind or stools with severe bloating), seek urgent medical attention
Uchigashima M, Cheung A, Suh J, Watanabe M, Futai K