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The most common GLP-1 side effects are gastrointestinal symptoms: nausea, vomiting, diarrhea, and constipation

Research suggests several beneficial mechanisms: Improved insulin sensitivity : Insulin resistance is a key driver of PCOS symptoms, and GLP-1 medications can enhance insulin action Weight loss effects : Even modest weight reduction (510% of body weight) can restore ovulation and regular cycles in women with PCOS [17] [18] Reduced androgen levels : Weight loss and improved insulin sensitivity often lead to decreased testosterone and other androgens Restoration of ovulation : Some women with PCOS who previously had absent periods may begin ovulating regularly NICE Clinical Knowledge Summary on PCOS recommends lifestyle modification and weight loss as first-line interventions for overweight women with the condition

10.1016/j.ijpharm.2024.124919 79 KuoY.-C.WangL.-J.RajeshR

Having significant antioxidant properties, they can decrease high blood pressure and concomitant comorbidities