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Safety still comes first Not everyone is a good candidate for GLP-1 treatment, and that remains true after approval
Kendzerska, T
In real-world practice, a SGLT2i and a GLP-1RA are more likely to be initiated sequentially rather than simultaneously, not only for economic reasons but also to improve medication adherence [1]
We don't have robust long-term data on: What happens to muscle mass and bone density over 5-10 years of use The impact on people who start these medications in their 20s or 30s Impact on fertility/reproductive outcomes Early data is showing that GLP-1 might help in PCOS, but what about long-term hormonal regulation
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