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When MRI was used to examine the brains of D2L2AD patients it was found that all showed enlarged ventricles, subependymal pseudocysts, and delayed gyration and myelination

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Subsequent analysis concluded that Epitalon modulates IL-1 signal transduction through the sphingomyelin route in cerebral cortex neuron membranes, as evidenced by variations in neutral sphingomyelinase activity in stress models [31]