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The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia

Although the exact mechanism of the connectivity of the gut-brain axis has not yet been elucidated, the evidence shows that gut microbiota plays an important role by producing immune factors, hormones, and metabolites that influence brain functioning