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The table below shows how each receptor relates to the reward and craving pattern this guide covers

de Azua IR, Gautam D, Jain S, Guettier J-M, Wess J

Peptides are short chains of amino acids linked together by peptide bonds, distinct from full proteins because they are much smaller but still specific enough to trigger a response once they attach to the right receptor

Why not the other options: Option C (phenytoin) historically the standard, but causes hypotension, cardiac arrhythmias (bradycardia, asystole), purple glove syndrome, and has complex pharmacokinetics (non-linear, protein binding displaced in uraemia)