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No specific biomarker has yet been identified to correlate with tinnitus in the absence of hearing loss, suggesting that a future direction in this field should be to discover and validate such a biomarker

Finally, the immunocomplexes were eluted with 20 L of 2 loading buffer, boiled for denaturation, and subjected to SDS-PAGE

Due to this dysfunction, there is an increase in the levels of glutamate in the synaptic cleft that activates the glutamate receptors which are present in the post-synaptic neurons (N-Methyl-D-aspartic acid (NMDA), -amino-3-hidroxi-5-methyl-4-isoxazolpropionic acid (AMPA), Kainate, and metabotropic glutamate (mGLUR) receptors), leading to excitotoxicity

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