We want to identify really useful peptides that can be leveraged and advanced as treatment for human diseases for which there is no solution at the moment. One potential prospect is MOTs-C, which Cohen discovered and has studied in Phase 1A and Phase 1B trials
This finding suggests possible non-monotonic dose-response (NMDR) effects, where low-dose exposure may produce different biological responses compared to higher exposure levels (79)
Potential Side Effects While there are no large randomized controlled studies, some common side effects reported include injection-site reactions (pain, erythema, swelling), headache, nausea, diarrhea, and rare hypersensitivity reactions
That being said, a particular form of carnitine , may increase the effectiveness of sildenafil in men with diabetes who had previously failed to respond to the drug, without serious adverse effects (mild gastric pain was reported)