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Bacterial-derived hyodeoxycholic acid (HDCA) promotes GLP-1 secretion by upregulating the expression of the bile acid receptor Takeda G protein-coupled receptor 5/G-protein-coupled bile acid receptor 1 and downregulating the expression of the bile acid receptor farnesoid X receptor in the gut [22]

They promote powerful GLP-1 appetite changes that quiet the non-physiological food noise, meaning you eat because your body needs nourishment, not because of compulsive thoughts or external cues

It instructs your body to support tissue repair, manage inflammation, and produce fresh collagen and elastin

As 100 mg/kg cinchonine showed a good glucose-lowering effect, this dose was used in subsequent experiments