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Additional technique considerations: The Association of Diabetes Care & Education Specialists (ADCES) generally recommends 4-mm pen needles for most patients regardless of body size, as they provide sufficient length for subcutaneous delivery while minimizing the risk of intramuscular injection

Patients with genetic variations that enhance GLP-1 receptor signaling may feel full and nauseated more intensely at standard dosesa signal to start lower and titrate slowly rather than push toward higher doses

The medication is formulated and licensed exclusively for subcutaneous use, as clearly stated in the Summary of Product Characteristics

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