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The cumulative annual cost often reaches $2,000-3,500 depending on frequency and clinic pricing

It is a well-established model for osteoarthritis, especially in cohorts of older age than we used here (52w) (Botter et al., 2011) and for the unhealthy loss in muscle (sarcopenia) and fat mass(Wijnhoven et al., 2005)

Additionally, this review systematically discusses the most recent pathophysiological mechanisms underlying these conditions, with a special emphasis on genetic susceptibility and chronic altitude illness (CMS and HAPH)

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