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Indication-specific trials

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Consequently, the genes interacting with the metabolics in the different subnetworks were used in STRING to build a giant network based on our seed genes enlarged with the MPI-derived DEPs, which were, consequently, analyzed in OmicsNet to construct a composite network consisting of metabolites and DEPs first entering MPIs and then the PPIs (analyzed with IntAct molecular interaction database) 5 with a targeted incorporation of TF protein interactions (TFPIs) (analyzed using TTRUST) 6

Cokorinos, E