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Phospho-protein kinase B (phospho-AKT) (Cat #9271), phospho-ribosomal protein S6 (phopho-RPS6K1) (Cat# #2215), and Glycerinaldehyde-3-phosphate-Dehydrogenase (GAPDH) (Cat #4691) were purchased from Cell Signaling Technologies (Danvers, MA, USA)

Although the event rate was low (4.6/1000 person-years for semaglutide, 7.9 for liraglutide and 1.0 for bupropion/naltrexone), there was a ninefold increased risk with GLP-1 receptor agonists overall

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