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nausea decreases with ongoing usage a steady weight loss occurs in some patients over 2 years (may be related to nausea & CNS-mediated loss of appetite) there is an increased risk of hypoglycemia when exenatide is used with a sulfonylurea The dose of the sulfonylurea may need to be reduced if hypoglycemia occurs when combined with exenatide Most serious : rare & sometimes fatal necrotizing or hemorrhagic pancreatitis When initiating patients on Byetta, watch for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back, which may or may not be accompanied by vomiting)

Anyone with a history of pancreatitis, severe gastrointestinal disease, or significant kidney impairment should raise these conditions with a clinician before any GLP-1 evaluation

Arthur Ronan, D.O., has been a board-certified Family Physician for over 20 years in Lansing, MI

But VIBES works similarly to another device, Moran says