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M.Brown-FrandsenK.ColhounH

Assumptions due to missing data are stated explicitly where usedmost importantly that menopausal status, baseline vulvovaginal symptoms, sexual activity, contraceptive use, and co-medications are frequently unreported in pharmacovigilance and trial summaries

Reduced physical activity : Some patients may experience temporary reductions in physical activity due to gastrointestinal side effects, potentially decreasing weight-bearing activity that helps maintain bone strength