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Acamprosate targets glutamate and GABA systems, two neurotransmitters deeply affected by chronic alcohol exposure, by decreasing excitatory activity and improving inhibitory signals
These findings align with previous reports that melatonin reduces ILC2-derived IL-5 and IL-13 in oxazolone-induced colitis models (65), suggesting a conserved anti-inflammatory effect of melatonin across tissues
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MAO-B serves as a target for PET imaging using Carbon-11 and Fluorine-18 radioligands, such as [ 11 C]-L-deprenyl and [ 18 F]SMBT-1, respectively, which have been translated into clinical applications (Rodriguez-Vieitez et al., 2016
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