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Kinetics, pharmacokinetics, and regulation of lcarnitine and acetyllcarnitine metabolism

Scaglia F: Carnitine deficiency

Chronic inflammation and persistently elevated glucose levels are common threads in cardiovascular disease, cognitive decline, and certain cancers

This exacerbates immune dysregulation by affecting macrophage polarization and the balance of T cell subsets, thereby participating in the pathological process of PH ( Metabolites achieve fine regulation of immune cell functions and inflammatory signals through multiple pathways such as metabolic reprogramming, tryptophan metabolism, and intestinal flora metabolism regulation