glp 1 with kidney disease GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of failure. Adverse events are mostly gastrointestinal Repurposing Diabetes Therapies in CKD:

Similarly, two effects of GLP-1 on the gut must be borne in mind: sympathetic nervous system activation and direct effects on receptors in the gut tissue

Time will tell if Ozempic really changes humanitys attempt at optimum health in an overburdened planet

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Br J Pharmacol 179(4):659676 Hernandez AF, Green JB, Janmohamed S, DAgostino Sr RB, Granger CB, Jones NP, et al (2018) Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial