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To construct the GPCR expression vectors, we utilized the Gateway system and subcloned 258 full-length human GPCR cDNAs from pDONR201 vectors 51 into pcDNA3.2/V5-DEST vectors (Thermo Fisher Scientific)

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For example, in a study of almost 17,000 people published in JAMA Ophthalmology in 2024, researchers found an increased risk of NAION among individuals prescribed semaglutide relative to those prescribed other medications to treat type-2 diabetes and obesity

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