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Hyperbaric oxygen therapy (HBO), a promising adjuvant for heatstroke-induced liver injury, synergizes with conventional therapy to mitigate hepatic dysfunction (evidenced by reduced ALT, AST levels) [85, 86], via anti-inflammatory effects (regulating immune cell balance, suppressing pro-inflammatory cascades), antioxidative actions (enhancing tissue oxygenation, reducing ROS-mediated lipid peroxidation), and improved coagulation (protecting hepatic microcirculation) [85, 86]

[DOI] [PubMed] [Google Scholar] 6.FDA

Extending half-life by 4060% means fewer injections, steadier fibroblast signaling, and higher cumulative dermal exposure at lower total peptide dose

One example of a GLP-1 and GIP dual agonist is Zepbound, an FDA-approved medication that works through both pathways under medical provider supervision