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1 Introduction Diabetic nephropathy (DN) is a chronic disease stemming from diabetes mellitus, characterized by microangiopathy and structural and functional renal alterations, standing as the foremost cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) ( Mitochondria, the double-layered membrane organelles renowned as the powerhouses of the cell, provide the main energy for cellular activities through oxidative phosphorylation(OXPHOS) ( Yin and Yang of the five zang viscera

But any combination should be supervised by a physician who can monitor your response and adjust dosing as needed

We treated male and female mice in parallel and report the sex-disaggregated data in Figure 1 and Supplemental Figure 1 (supplemental material available online with this article