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Gerstein HC, Colhoun HM, Dagenais GR, et al

While adipose tissue reduction is therapeutically desirable, disproportionate loss of lean mass may lower resting energy expenditure, impair functional capacity, and potentially compromise long-term metabolic durability

Effectiveness and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in type 2 diabetes: an Italian cohort study