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Lund A, Vilsboll T, Bagger JI et al (2011) The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

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They should mainly be used as second-line therapy as add on to metformin in patients with type 2 diabetes who have no pre-existing cardiovascular disease and have a therapeutic goal to avoid hypoglycaemic events

So unless you include regular exercise as part of your weight loss program, the weight you lose while taking Ozempic, Wegovy, Mounjaro or Zepbound will include both muscle and fat, but the weight you will regain after stopping the GLP-1 will be mostly fat, leaving you metabolically even worse off than when you started