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Experiments were conducted using DIO male C57BL/6J mice (Janvier Labs) kept on a HFHS diet (58 kcal% fat, D12331i, Research Diets) from 8 weeks of age

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Because side effects like nausea and fatigue can directly hinder the ability to engage in consistent strength training and consume adequate protein [Insight 6 Elaboration], managing them effectively becomes an enabling factor for achieving the muscle preservation goal

Int Immunopharmacol 119:110239