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10.1016/j.molcel.2021.08.018 57 LiJ.HanF.MaJ.WangH.PanJ.YangG.et al (2021)

For the vast majority of people, the answer is a resounding yes

Crucially, they trigger insulin release only when glucose is already present in the bloodstream, minimizing the risk of dangerous hypoglycemia seen with some older diabetes drugs

[1] [2] Whilst these mechanisms contribute to improved glycaemic control and weight reduction, they also account for one of the most commonly reported adverse effects: nausea