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* Do not use on broken or severely irritated skin

Despite consuming food equivalent to half of their body weight, these lizards can effectively regulate blood glucose levels due to the presence of exendin-4.[35] Exendin-4 shares structural similarity with GLP-1, binds to its receptor with comparable affinity, but has a longer half-life than GLP-1.[36] The discovery led to the development of exenatide, the first GLP-1 analog for type 2 diabetes,[37] followed by subsequent analogs with improved pharmacokinetics

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There is no validated dose-conversion ratio between tirzepatide and semaglutide