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Description

In healthy individuals, this effect is therapeutic and typically well-tolerated with appropriate dose titration

Potential signals of serious risks/new safety information identified by the FDA adverse event reporting system (FAERS)

March 15, 2023

These observations were corroborated by single-cell calcium imaging studies in slices of arcuate nuclei, demonstrating that GLP-1MK-801 inhibits the NMDA-induced intracellular calcium surge relative to GLP-1 alone (Extended Data Fig