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8% say they suffered from gallbladder injuries, with some of these patients requiring surgical removal of gangrenous tissue

The ensuing negative feedback loop may involve not only EECs but also Paneth cells and intestinal intraepithelial lymphocytes, as these cells have been reported to express the receptor for GLP-1 (namely GLP-1R), and loss of GLP-1R increases the severity of DSS-induced intestinal injury8, 9

UK Chief Medical Officers recommend no more than 14 units weekly, spread over several days, with some alcohol-free days each week

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