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By acting as a precursor of phytochelatins, GSH helps in the chelating of toxic metals/metalloids which are then transported and sequestered in the vacuole

R 3 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl-OR S , optionally substituted C 1 -C 6 alkylC 3 -C 6 cycloalkyl, optionally substituted C 2 -C 7 heterocycloalkyl, C 1 -C 6 alkyl-CO 2 R 6 , C 1 -C 6 alkyl-C(O)NR 5 R 6 , or R 2 and R 3 together with the nitrogen to which they are attached form an optionally substituted C 2 -C 7 heterocycloalkyl ring

Regulatory status Retatrutide and similar peptides are investigational not approved by the FDA or any regulator

Camilleri was a co-author on a third study being presented Monday at Digestive Disease Week that looked at gastroparesis with GLP-1 medications