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[5] Regular monitoring of estimated glomerular filtration rate (eGFR) is appropriate for patients on DOACs, with warfarin often preferred in severe renal impairment or end-stage renal disease depending on the indication

A standard 3 mL peptide vial comfortably holds up to about 3 mL, and many so-called "10 mL" vials are only partially filled by design to leave headspace

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