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This severe glutathione deficit was accompanied by elevated ventricular lactate, a clear biomarker indicating that the brains of these patients are relying on highly inefficient, oxygen-deprived anaerobic metabolism due to mitochondrial stress
So, it wasnt yet standard of care, and access to SGLT2 inhibitors was still limited
Garca-Minguilln CJ, Fernandez-Ballart JD, Ceruelo S, et al
Effect of additional oral semaglutide vs sitagliptin on glycated hemoglobin in adults with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea: PIONEER 3
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