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Several collagen-based skin substitutes are commercially available and leverage the wound-healing potential of collagen [102,103,104]

Copper (I) oxide causes dose-dependent decrease in the viability of airway epithelial cells by impairing the activities of catalase and glutathione reductase , generating reactive oxygen species , and increasing the levels of 8-isoprostane and the ratio of oxidized glutathione

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Other enzymes that are involved in the generation and/or utilization of TCA cycle intermediates within the nucleus include isocitrate dehydrogenase 3 (IDH3), isocitrate dehydrogenase 1 (IDH1), aconitase 2 (ACO2), the A (SDHA) and B (SDHB) subunits of the succinate dehydrogenase (SDH) complex, and several amino transferases such as glutamate-oxalate transaminase 1 (GOT1)