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Further medicinal chemistry optimization to improve structure activity relationship and potency as well as safety and toxicity, pharmacokinetic (bioavailability, half-life and biodistribution) and rodent in vivo studies will follow to determine the compounds potential to become suitable candidates for further development

It's important to note that these personality shifts don't indicate permanent changes to an individual's core character

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Glucose-dependent insulinotropic polypeptide (GIP) receptor enhances insulin release in response to food intake and may contribute to weight loss