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Ferroptosis is regulated by GPX4, an enzyme that reduces lipid hydroperoxides within biological membranes 26

The risks include irritation or injury to the rectum or intestines, electrolyte imbalances, and infection

A combination of vitamin E (1000 IU/day) and pentoxifylline (800 mg/day) completely reversed a case of radiation-induced cervicothoracic fibrosis in a 67-year-old woman after an 18-month course of treatment