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Mechanism of action when taken orally: Even though some oral glutathione is degraded in the gut, the resulting amino acids (cysteine, glycine, glutamate) serve as substrates for de novo glutathione synthesis in tissues

IL-6 binds to the secreted form of IL-6R (sIL-6R), forming an IL-6-sIL-6R complex that interacts with the transmembrane protein IL-6 receptor subunit- (gp130

Studies administering 3 gm/day to 6 gm thrice daily over 1 to 24 months reported significant improvements, corroborated by recent trials with doses up to 2 gm/day without adverse effects