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RSC Med Chem

BPC-157 (Body Protection Compound-157), derived from a protective protein naturally found in gastric juice, promotes angiogenesis, stimulates fibroblast activity and collagen remodeling, and modulates the nitric oxide pathway to improve local blood flow

Taken together, this also demonstrates that Fc-engineered human IgG variants with altered binding to FcRn behave differently in human and murine model systems, which highlights the importance of accounting for cross-species differences when studying Ab-based therapeutics and FcRn biology [101,102,103]

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