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There may be a higher risk of nutritional imbalance from regular consumption of products aimed at a gluten-free diet (Miranda et al, 2014) and avoidance of cereal products such as wheat will reduce the opportunity for dietary betaine

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If FDA-approved medications in this class are available

10.1080/07853890.2023.2191218 Summary Keywords diabetes, chronic kidney disease, gum acacia, melatonin, betaine, flaxseed Citation Al Zaabi M, Al Suleimani Y, Ali H, Ali BH and Al Maskari R (2025) The effect of different combinations of flaxseed, melatonin, gum acacia, and betaine on diabetic rats with adenine-induced chronic kidney disease