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Though there has been some preliminary data that GLP-1RAs might protect against cognitive decline and dementia, the research is still in clinical trials
1-8 Recent European Society of Cardiology guidelines for the management of cardiovascular disease (CVD) in patients with diabetes state that GLP-1 RAs (lixisenatide, liraglutide, semaglutide, exenatide extended release [ER], dulaglutide, efpeglenatide) should be considered for glucose-lowering treatment in patients with T2D at risk of or with heart failure (HF
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Thus, disruption of the gene encoding either of these -type TrxRs is compensated by a partial re-distribution of product from the other gene into the deficient sub-cellular compartment (Meyer et al., 2008
