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Reappraisal of GIP pharmacology for metabolic diseases

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Santalla et al., 2014) and not in CPTII deficiency individuals ( An extensive description of the methods for diagnosing CPTII deficiency (i.e., clinical presentation, pathobiochemical characteristics, molecular genetic aspects, detectable biomarkers and genotype-phenotype analysis) has been recently published by Sigauke et al., 2003) or functional evaluations, able to show abnormalities in lactate levels, VO 2 max capacity and respiratory exchange ratio (R) during an ergometric incremental test, which may underline the defective mitochondrial oxidative functionality (Tarnopolsky, 2016)