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Despite its growing popularity among athletes and its wide availability through non-regulated sources, there is minimal human data available

As an example, tendon tissue is composed primarily of tendon fibroblastic cells and extracellular matrix, which contains predominantly type I collagen, type III collagen and glycoproteins (Fukuta et al

Peptides play various roles in the body, including acting as hormones, neurotransmitters, and cell signalling molecules

These combined effects are particularly intriguing for orthopedics because many musculoskeletal injuries (Achilles tendon ruptures, rotator cuff tears, chronic tendinopathies) occur in precisely those areas where blood flow is limited and healing is frustratingly slow