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Future studies should explore more effective combinations of lifestyle interventions and pharmacotherapy, with emphasis on maintaining metabolic health and preserving lean mass, particularly through nutritional support and resistance training, among people at higher risk of sarcopenia

J Exp Med 211:233244 Boado RJ, Zhang Y, Zhang Y, Pardridge WM (2007a) Humanization of anti-human insulin receptor antibody for drug targeting across the human bloodbrain barrier

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And it supports bone health, which prevents one of the most common forms of collateral damage during aggressive weight loss