Rather than recommending cessation of GLP-1 receptor agonists prior to FDG PET-CT, which might disrupt metabolic homeostasis or compromise chronic disease control, experts suggest meticulous documentation of patient pharmacotherapy in imaging requisitions and reports
A tricky thing with semaglutide is that GI symptoms (such as nausea, vomiting, and diarrhea) are the most common side effectsand each one can dehydrate you, indirectly contributing to fatigue
Discussion Since 2020, these data suggest strong uptake of GLP-1-based drugs for overweight and obesity, including substantial off-label use of GLP-1 drugs that are approved for T2D only
Corticosteroids promote: Fat redistribution , causing central (truncal) obesity and the characteristic "cushingoid" appearance with prolonged use Fluid retention , leading to weight gain that may not reflect true fat accumulation but can be discouraging Muscle protein breakdown , reducing lean body mass and potentially lowering metabolic rate Insulin resistance , making weight loss more difficult The magnitude of these effects is generally dose- and duration-dependent