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long-term overdose effects due to increased blood calcium levels include renal failure and metastatic calcifications (especially in the kidneys, as kidney stones) Vitamin E: muscle weakness, gastrointestinal disturbances, interference with blood clotting Vitamin K: hemolytic anemia, hyperbilirubinemia, and associated jaundice, particularly in impacted infants Dangers and risks of vitamin overdose Many short-term side effects of vitamin overdose result in symptoms like gastrointestinal disturbances, changes in liver and kidney function, and some mentation changes

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Immune cells express vitamin D receptors, and adequate D3 status supports the production of antimicrobial peptides that serve as your body's first line of defense against pathogens