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Description

Drugs that exhibited statistically insignificant differences compared to the 0 Gy control (hits) with the glutathione assay were then tested with the senescence assay to discover library members that were efficacious in both assays (double hits)

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Among these, the kynurenine pathway is notably implicated in modulating immune responses and has been increasingly associated with chronic inflammatory conditions 74

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References: (1) Stanley TL, Feldpausch MN, Oh J, Branch KL, Lee H, Torriani M, Grinspoon SK

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[DOI] [PubMed] [Google Scholar] 28.OBrien CA, Pollett A, Gallinger S, Dick JE

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