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So, in this case, the water retention can be an indirect side effect of the peptide's primary effect on appetite

Curcumin as a therapeutic agent: The evidence from in vitro, animal and human studies

Magge A

the compound 1 used in the patent is not easy to obtain (the synthesis steps are relatively more, the cost is higher) and has low purity (in the process of preparing the compound 1 from the compound 6 in the previous step, the N-succinimide is easily removed while the tert-butyl group is removed)