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At the molecular level, erianin not only blocks the activation of the PI3K/AKT pathway, but also effectively reverses the epithelial-mesenchymal transition (EMT) of GC cells by inhibiting LKB1/SIK2/3/PARD3 signal transduction (38)
Vitamin K and cancer
The LC/MS portion of the platform was based on a Surveyor HPLC and a Thermo-Finnigan LTQ Fmass spectrometer (Thermo scientific, Waltham, Massachusettes, USA), which consisted of an electrospray ionization (ESI) source and linear ion-trap (LIT) mass analyzer
The crude extract exhibited significant acetylcholinesterase (AChE) inhibitory activity with an IC value of 106.0163 g/mL, indicating effective modulation of cholinergic function
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