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249,306,341-343 Several meta-analyses (of predominantly cohort studies) have shown that metabolic bariatric surgery confers significant improvement in cardiovascular risk factors including blood pressure, glycaemia, lipids and waist circumference, compared with medical management
For the therapy of AD, antidiabetic peptides, such as insulin and GLP-1 receptor agonist, have been tested for their potential in promoting memory and learning functions by facilitating the insulin receptor signaling and glucose transport in hippocampal neurons (Kamei et al., 2018)
In contrast, tirzepatide, a dual GLP-1 RA (GIP/GLP-1 RA) [1], was associated with a markedly larger effect, with a pooled mean difference of - 23.80 events/hour (95% CI: 29.62 to 17.98
More serious symptoms that need prompt attention include: Gardocki RJ, Park AL
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