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De, S., et al., Unraveling the Ties: Type 2 Diabetes and Parkinsons Disease - A Nano-Based Targeted Drug Delivery Approach

When people first go on these medications they lose muscle and fat (which is natural), but if they go off of them and gain weight back, its all fat

A 240-pound man burning 2,400 calories at rest plus an estimated 200-300 extra calories from glucagon-driven thermogenesis is operating at a substantial daily deficit even with moderate food intake