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Weight loss exceeding two pounds weekly after the first month might seem like good news, but it increases risks

Compensatory overproduction of pancreatic islets and eventual development of hyperinsulinemia, result in elevated hepatic synthesis and accumulation of total cholesterol (TC) and elevated low-density lipoprotein (LDL) levels, leading to inactivation of the enzyme LDL lipase, which is critical for cholesterol clearance