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The SURPASS clinical trial program that included more than 10,000 patients in five pivotal trials indicated that tirzepatide provided a reduction in HbA1c (maximum of 2.4) (versus 1.5-1.8) and weight loss (maximum of 22.5) of baseline body weight at the highest dose of 15mg

The first main difference is that while TiO2 gives a nice broad spectrum protection, Zinc Oxide has an even nicer and even broader spectrum protection

Thus, L-type VDCCs played a minor role as mediators of sustained Ca 2+ influx stimulated by JWU-A021